Xavant
Stimpod NMS450X+

AMG and EMG in one handheld unit

A handheld quantitative NMT monitor that supports both acceleromyography and electromyography. The method of measurement is a choice you make case by case at the point of care, not one that is fixed at purchase.

Request a theatre evaluation
0Baseline calibrationsNone required for the AMG sensor.
2Monitoring methodsAMG and EMG in one handheld device, chosen case by case rather than at purchase.
3Clinical viewsWaveform, quantitative measurement and full-case trend, on one touchscreen.
8Operating modesPost-tetanic count in deep block through to quantitative TOF at recovery.
Clinical capability

Set up, and start monitoring.

Three views to follow the whole case: the waveform, the ratio and the trend.

Set-up

Apply the electrode, press start, and you are monitoring.

No baseline calibration for the AMG sensor, and no waiting for one. The reading is quantitative.

1
Waveform
EMG waveform screen

EMG waveform

Inspect the shape of the measured response.
2
Measurement
Quantitative TOF screen

Quantitative TOF

Monitor block depth through the case.
3
Trend
Full-case trend screen

Full-case trend

Confirm recovery before extubation.
Train-of-four ratio0.9

A key recovery threshold in the guidance. Interpretation depends on the monitoring method.

Quantitative assessment

Make recovery measurable.

Train-of-four ratio
00.40.91.0
Read the number in context. See the guidance below.

An objective train-of-four ratio complements clinical assessment. Above approximately 0.4, fade becomes difficult to distinguish by sight or touch. Quantitative measurement provides the numerical response.36

Residual neuromuscular block remains a recognised clinical problem.12 Use the measured response alongside the full clinical assessment.

Read the guidance →
Published evidence

Reversal is not measurement.

A multicentre study across five university-affiliated teaching hospitals compared residual block after neostigmine and after sugammadex, in a setting where dosing was not guided by neuromuscular monitoring. Train-of-four ratio was measured after tracheal extubation.

After neostigmine
23.9%
of patients had a train-of-four ratio below 0.9 after extubation. 95% CI 16.2% to 33.0%.
0%35%
109 patients, average dose 33 µg/kg
After sugammadex
4.3%
of patients had a train-of-four ratio below 0.9 after extubation. 95% CI 1.7% to 9.4%.
0%35%
117 patients, average dose 2.7 mg/kg

Sugammadex reduced residual block. It did not remove it.

Kotake Y, Ochiai R, Suzuki T, et al. Reversal with sugammadex in the absence of monitoring did not preclude residual neuromuscular block. Anesthesia & Analgesia 2013;117(2):345–351.5 Prospective multicentre observational study conducted in Japan, where routine practice at the time did not involve monitoring devices to guide dosing. The authors concluded that the finding underscores the importance of neuromuscular monitoring even when sugammadex is used.

Neuromuscular recovery rests on a number, not an estimate.

The Stimpod NMS450X+ measures the train-of-four ratio objectively and records it, so recovery is demonstrated and documented before extubation.

Published evidence

Documented recovery before extubation: from 1% to 93%.

What changed in one department that put quantitative monitors in every anaesthetising location and built a practice-change programme around them: equipment trials, education, clinical decision support with real-time alerts, and an ongoing performance metric.

November 2016
1%
of anaesthesia records documented a train-of-four ratio at or above 0.90 before extubation. 2 of 172 cases.
December 2020
93%
of records documented it, after quantitative monitors were placed in every anaesthetising location. 250 of 269 cases.

Reversal reduces the risk. Only measurement tells you about the patient in front of you.

Weigel WA, Williams BL, Hanson NA, et al. Quantitative neuromuscular monitoring in clinical practice: a professional practice change initiative. Anesthesiology 2022;136(6):901–915.7 A single-centre retrospective review of a practice change programme, not a randomised trial. The figures above are documentation of recovery before extubation, which is a process measure: the authors are explicit that it is an intermediate outcome and only one of many factors contributing to patient outcomes.

Sensor selection

Choose the sensor that fits the case

One device, two monitoring technologies. Select on surgical setup and clinical need.

EMG electrode applied along the arm to the hand
Tucked arm
EMG electrode
Robotic & laparoscopic surgery

EMG does not depend on free thumb movement. It measures the muscle's electrical response, which makes it an option when the arm is tucked or access to the hand is restricted. The flexible electrode fits the left or right hand, maintains adhesion through long procedures with frequent patient movement, and provides continuous closed-circuit confirmation. Single-use. Adult and paediatric sizes.

AMG accelerometer sensor on the thumb with arm electrodes
Open arm
AMG sensor
Cost-sensitive & high-turnover surgery

A reusable three-axis sensor measures the response through movement, so the thumb needs to be free. No baseline calibration is required for the AMG sensor, and it takes standard ECG electrodes your hospital already stocks. Three monitoring points: hand at the ulnar nerve, toe at the posterior tibial nerve, face at the facial nerve.

Monitoring site matters. For assessment of recovery before extubation, the guidance below specifies the adductor pollicis.

The standard

What the guidelines recommend

Both UK and European guidance set the same threshold.

01

Association of Anaesthetists

Quantitative neuromuscular monitoring whenever neuromuscular blocking drugs are given, continued until a train-of-four ratio above 0.9 is confirmed.3

02

European Society of Anaesthesiology and Intensive Care

Continue quantitative monitoring until a train-of-four ratio of more than 0.9 has been attained, measured at the adductor pollicis.4

Two bodies, one recovery target: above 0.9, confirmed quantitatively. Apply the guideline threshold for the measurement method and site.

In practice that means a device that produces the ratio objectively and records it. Not a stimulator, and not an inference from the dose given.

Stimpod X-Link module mounted on an IV pole
Integration

Connect monitoring to your workflow.

Optional record integration

Hospital records. The optional X-Link module connects the Stimpod directly to your hospital record system, supporting HL7 and FHIR, with smart charging and real-time data transfer. Confirm interfaces, accessories and local installation with your clinical engineering or IT team.

No third-party middleware required. IHE standards supported. Flexible mounting for an IV pole or permanent installation.

Technical details

Specifications

Detailed information for procurement and clinical evaluation.

Device

Display3.5″ colour touchscreen.
Dimensions174 × 90 × 35mm, handheld.
Weight265g with battery, 195g without.
BatteryRemovable rechargeable Li-ion. Up to 35 hours of continuous monitoring at default display intensity, and up to 32 hours in EMG mode.
Operating modesAUTO, TOF, PTC, SMC, DEP, ST, DB, TET.
RegulatoryCE marked. Notified Body 1639 (SGS Belgium).

EMG electrode

DesignRipple design. Fits left or right hand, adult and paediatric.
MaterialSoft dermatoid. Maintains adhesion through long procedures.
DetectionPeak-to-peak and area under curve.
CircuitContinuous closed-circuit confirmation.

AMG sensor

TypeReusable 3-axis accelerometer.
Monitoring sitesUlnar nerve (hand), posterior tibial nerve (foot), facial nerve.
Set-upRapid patient set-up, with immediate clinical use.
Running costReusable, so suited to high-volume settings.

X-Link integration

FunctionOptional module for electronic patient record (EPR) connectivity.
ConnectionDirect to the hospital network. No third-party middleware.
StandardsHL7, FHIR and IHE.
PowerSmart charging, which extends battery life.
MountingIV pole or permanent installation.
Next steps

See the Stimpod NMS450X+
in your theatre.

Arrange a trial or clinical demonstration with the LP Med team.

Request a theatre evaluation

Opens an email to info@lpmed.co.uk. It helps to include your hospital, the theatres involved and rough timing.

References

  1. Murphy GS, Brull SJ. Residual neuromuscular block: lessons unlearned. Part I: definitions, incidence, and adverse physiologic effects of residual neuromuscular block. Anesthesia & Analgesia 2010;111(1):120–128. doi:10.1213/ANE.0b013e3181da832d Back to the text
  2. Rodney G, Raju P, Brull SJ. Neuromuscular block management: evidence-based principles and practice. BJA Education 2024;24(1):13–22. doi:10.1016/j.bjae.2023.10.005 Back to the text
  3. Klein AA, Meek T, Allcock E, et al. Recommendations for standards of monitoring during anaesthesia and recovery 2021: Guideline from the Association of Anaesthetists. Anaesthesia 2021;76(9):1212–1223. doi:10.1111/anae.15501 Back to the text
  4. Fuchs-Buder T, Romero CS, Lewald H, et al. Peri-operative management of neuromuscular blockade: A guideline from the European Society of Anaesthesiology and Intensive Care. European Journal of Anaesthesiology 2023;40(2):82–94. doi:10.1097/EJA.0000000000001769 Back to the text
  5. Kotake Y, Ochiai R, Suzuki T, Ogawa S, Takagi S, Ozaki M, Nakatsuka I, Takeda J. Reversal with sugammadex in the absence of monitoring did not preclude residual neuromuscular block. Anesthesia & Analgesia 2013;117(2):345–351. doi:10.1213/ANE.0b013e3182999672 Back to the text
  6. Viby-Mogensen J, Jensen NH, Engbaek J, Ording H, Skovgaard LT, Chraemmer-Jørgensen B. Tactile and visual evaluation of the response to train-of-four nerve stimulation. Anesthesiology 1985;63(4):440–443. doi:10.1097/00000542-198510000-00015 Back to the text
  7. Weigel WA, Williams BL, Hanson NA, Blackmore CC, Johnson RL, Nissen GM, James AB, Strodtbeck WM. Quantitative neuromuscular monitoring in clinical practice: a professional practice change initiative. Anesthesiology 2022;136(6):901–915. doi:10.1097/ALN.0000000000004174 Back to the text